Opportunity Information: Apply for 72067418RFA00002

USAID South Africa is offering a discretionary funding opportunity called "Preventing HIV/AIDS in Vulnerable Populations in South Africa" (PHVP) for the 2018-2023 period. The overall aim of the activity is to help South Africa accelerate and sustain HIV epidemic control by delivering high-impact HIV prevention services alongside care and support. In practical terms, the program is designed to reduce new infections while also strengthening the health and wellbeing of people and communities that face elevated HIV risk or are already living with the effects of the epidemic, with a strong emphasis on children, adolescents, and other vulnerable groups.

The opportunity is structured around four main objectives that together cover prevention, protection, and support. First, it seeks to improve the health and wellbeing of orphans and vulnerable children (OVC), along with adolescents and youth who are living with HIV, affected by HIV in their families or communities, or otherwise vulnerable to infection. This objective typically points to integrated services that address both clinical and non-clinical needs, recognizing that HIV outcomes are shaped by factors such as household stability, caregiver support, access to social services, and consistent linkage to health care. Second, the activity prioritizes school-based HIV prevention and gender-based violence (GBV) prevention, reflecting the role schools can play as a consistent platform for prevention education, risk reduction, and protective interventions for learners. Third, it aims to scale up community-based violence prevention interventions and strengthen linkages to response services, highlighting the connection between violence and HIV risk and the importance of having clear pathways from prevention to survivor-centered support. Fourth, it focuses on preventing new HIV infections among priority populations, signaling targeted prevention approaches where incidence and vulnerability are concentrated.

A key feature of the activity is its reliance on evidence-based interventions, meaning applicants are expected to propose approaches that have been shown to work in reducing HIV risk, supporting adherence and retention in care, and mitigating the social and economic impacts of HIV on families. The description emphasizes interventions that reduce the impact of HIV on children, adolescents, and their families, and also explicitly calls out prevention for adolescent girls and young women (AGYW), including those who have experienced violence. In addition, the activity includes a focus on migrant and mobile populations in select sub-districts, acknowledging that mobility can increase vulnerability and disrupt access to prevention tools and continuity of care.

Programmatically, the activity is organized into four core components. Component 1 covers services for orphans, vulnerable children, adolescents, and youth, which often includes a mix of psychosocial support, linkage to HIV testing and treatment, adherence support for those living with HIV, and wraparound services that improve safety and stability. Component 2 addresses school-based HIV prevention and GBV prevention, which can include age-appropriate prevention programming, initiatives to reduce violence and harassment in and around schools, and mechanisms for referral when learners need health or protection services. Component 3 is centered on community-based violence prevention and building strong linkages to response, pointing to interventions that change community norms, reduce perpetration and victimization, and ensure survivors can access medical care, psychosocial support, and legal or protection services as appropriate. Component 4 targets prevention of new HIV infections among priority populations, which typically implies a combination prevention approach tailored to local epidemiology and risk patterns, potentially including demand creation, risk reduction counseling, linkage to biomedical prevention and testing services, and strategies that address structural barriers to access.

From a grants and compliance perspective, this is a cooperative agreement, which generally means USAID anticipates substantial involvement in the implementation and oversight of the award compared to a standard grant. The funding opportunity number is 72067418RFA00002, and it falls under the health funding activity category with CFDA number 98.001. The posting lists an award ceiling of $150,000,000 and anticipates up to 8 awards, indicating a large, multi-award program that could support multiple implementers or consortia working in different geographies or along different technical components. The opportunity was created on November 27, 2017, with an original closing date of January 29, 2018. Eligibility is listed broadly as "Others," with additional eligibility details referenced as being in the full opportunity text, which commonly means prospective applicants would need to consult the official solicitation for specific organizational requirements, partnership expectations, and any restrictions.

Overall, PHVP is framed as a comprehensive HIV prevention and support activity designed to tackle both immediate HIV risks and the underlying drivers that shape vulnerability, especially for children, adolescents, and young women. The design combines household and community support, school-based prevention, violence prevention and response linkages, and targeted prevention for populations at heightened risk, all with the explicit goal of sustaining epidemic control gains in South Africa.

  • The Agency for International Development, South Africa USAID-Pretoria in the health sector is offering a public funding opportunity titled "Preventing HIV/AIDS in Vulnerable Populations in South Africa" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
  • This funding opportunity was created on Nov 27, 2017.
  • Applicants must submit their applications by Jan 29, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $150,000,000.00 in funding.
  • The number of recipients for this funding is limited to 8 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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